Variations in surgical procedures for hind limb ischemia mouse models result in differences in collateral formation
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Variations in surgical procedures for hind limb ischaemia mouse models result in differences in collateral formation.
OBJECTIVE To identify the optimal mouse model for hind limb ischaemia, which offers a therapeutic window that is large enough to detect improvements of blood flow recovery, for example, using cell therapies. MATERIALS AND METHODS Different surgical approaches were performed: single coagulation of femoral and iliac artery, total excision of femoral artery and double coagulation of femoral and ...
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تاریخ انتشار 2011